Holy Jumpin' up-and-down-Martha!!!! Estrogen side effects. One could become a skinny, drooling, cramped up and bloated, bleeding, blind, yellow vomiting mess with an increased sex drive. Oh, goody. "For a good time call Estrogen Esther while she can still hear her phone ring."

http://www.premarin.org/estrogen.html

Possible Side Effects:

The most common side effects include enlargement or tenderness of the breasts (both sexes), swelling of the ankles and legs, loss of appetite, weight changes, retention of water, nausea, vomiting, abdominal cramps, and feeling of bloatedness. The estrogen patch can cause skin rash, irritation, and redness at the patch site.

Less common side effects are bleeding gums, breakthrough vaginal bleeding, vaginal spotting, changes in menstrual flow, painful menstruation. pre-menstrual syndrome, no menstrual period during and after estrogen use, enlargement of uterine fibroids, vaginal infection with Candida, a cystitis-like syndrome, mild diarrhea, jaundice or yellowing of the skin or whites of the eyes, rash, loss of scalp hair, and development of new hairy areas. Lesions of the eye and contact-lens intolerance have also been associated with estrogen therapy. You may experience migraine headache, mild dizziness, depression, and increased sex drive (women) or decreased sex drive (men).

Rare side effects include stroke, blood-clot formation, dribbling or sudden passage of urine, loss of coordination, chest pains, leg pains, difficulty breathing, slurred speech, and vision changes. Men who receive large estrogen doses as part of the treatment for prostate cancer are at a greater risk for heart attack, phlebitis, and blood clots in the lungs.