"Nihilism is the belief that all values are baseless and that nothing can be known or communicated. It is often associated with extreme pessimism and a radical skepticism that condemns existence. A true nihilist would believe in nothing, have no loyalties, and no purpose other than, perhaps, an impulse to destroy."
From http://belmontclub.blogspot.com/

"3. The Buddha answered, “A Bodhisattva should keep this in mind: All creatures, whether they are born from the womb or hatched from the egg, whether they transform like butterflies or arise miraculously, whether they have a body or are purely spirits, whether they are capable of thought or not capable of thought: All of these I vow to help enter nirvana before I rest there myself!

“But keep in mind, Subhuti, that in reality there is no such thing as an I who helps, and no such thing as an other whom I help. A Bodhisattva who does not recognize this reality is no true Bodhisattva! "
http://www.ship.edu/~cgboeree/diamondsutra.html

A little later on:
"6. Subhuti asked, “Lord, will there always be people who understand your message?”

Buddha answered, “Don’t doubt it, Subhuti! There will always be people who, hearing the message, will adhere to the precepts and practice our way. Our message will reach people simply because it is true! There will come a time when many will no longer need words, but will be beyond words. We must all strive to go beyond the words, because words can be clung to, and we should not cling to things. Understand that the words of the Buddha are like a raft built to cross a river: When its purpose is completed, it must be left behind if we are to travel further! "

I would loosely say buddhism and nihilism are sort of similar but going the opposite direction.

Anyone want to add their 2 cents?