There's a difference between a civilized nation having nuclear weapons and lunatic regimes having them, as the article you link to states quite clearly.

Iran is already breaking the Non-Proliferation treaty, so I suspect declaring the Middle East a "nuclear-free" zone would have had as much effect on that nation as outlawing guns has on criminals.

Nobody is worried about Israel or India suddenly deciding to wipe all the Muslim nations off the face of the Earth. Iran has openly announced their intention to destroy Israel.

I'm having a lot of difficulty believing that if Israel had no nuclear arms, that countries like Libya, Iran, Iraq, and others would not have had any ambition to possess them.