Quotes from the article "Listening for Pioneer 10":

Centauri Dreams is following the Pioneer 10 story with great interest, and not just in terms of the anomalous effects that continue to keep this mission in the news. Ponder that Pioneer 10 was launched in 1972 and consider that even with the technologies of its day, the probe may still be able to communicate with Earth.

We have learned so much in the interim about hardened electronics and autonomous self-repair that there is reason to believe probes to even remoter locations in the Kuiper Belt and beyond are feasible providing we can solve the propulsion conundrum.

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It’s too late for New Horizons, of course, but any followup Pluto/Kuiper Belt mission would have such an opportunity. On that score, see T. Bondo, R. Walker, A. Rathke et al., “Preliminary Design of an Advanced Mission to Pluto,” scheduled to appear in the proceedings of the 24th International Symposium on Space Technology and Science, Miyazaki, Japan, June 2006, and already available online (PDF warning).

http://www.centauri-dreams.org/?p=534