Thank god we have someone to bring dignity back to the white house!

Family
Poppy, 41, Old Man - George H. W. Bush
Bushie - Laura Bush (this is a mutual nickname)

Foreign Leaders
Pootie-Poot - Vladimir Putin, President of Russia
Landslide - Tony Blair, Prime Minister of the United Kingdom
Dino (short for Dinosaur) - Jean Chrétien, Former Prime Minister of Canada

Staff
Boy Genius (positive), Turd Blossom (negative) - Karl Rove, Senior Advisor
The World's Greatest Hero (positive and negative) - Colin Powell, Secretary of State
Big O (current), Pablo (former) - Paul O'Neill, Former Secretary of the Treasury
Ari-Bob - Ari Fleischer, White House Press Secretary (through July 2003)
High Prophet, Hurricane Karen - Karen Hughes, Special Advisor; Director of Communications under Texas Governor George W. Bush
The Blade - Mitch Daniels, Director, Office of Management and Budget
Big Country - Joe Allbaugh, FEMA director
Brownie - Michael D. Brown, DHS undersecretary for emergency preparedness and response (FEMA director within DHS)
Tree Man - Unnamed forest service official

Politicians
Pablo - Paul Wellstone Democratic Senator, Minnesota
Big George - George Miller, Democratic Congressman, California
Freddy Boy - Fred Upton, Republican Congressman, Michigan
Congressman Kickass - John Sweeney, Republican Congressman, New York
Big O - Olympia Snowe, Republican Senator, Maine
Nellie (former), Benney (former), Benator (current) - Ben Nelson, Democratic Senator, Nebraska (Daily Show, 02/28/05)
Ellis - Chuck Schumer, Democratic Senator, New York

Journalists
The Cobra - Maureen Dowd
Stretch/Little Stretch - David Gregory, NBC
Stretch - Dick Keil, Bloomberg News
Super Stretch - Bill Sammon, Washington Times
Factor (current), Big O (former) - Bill O'Reilly
(actual nickname claimed to be unprintable) - Dana Millbank of the Washington Post

Others
Kenny Boy - Kenneth Lay
Weadie, Weadnik - author Doug Wead