Sure...I guess...
I realize Knight's making his proposal as a thought-experiment intended to inspire others. Lord knows, America could use some grade-A large inspiration on the space exploration front.
But this whole "one-way trip" thing that we've seen from Aldrin and now Knight...I dunno. At least Zubrin allowed for the very basic human desire to come home.
If we'd asked Aldrin to spend the last half of his life on the moon building a settlement, without any reasonable hope that he'd ever return to earth, would he have gone? He may be a tough bird, but some things are beyond the pale.