I suspect almost the same could have been said when the REA came into being.
You have an impressive background in the area. I do not doubt your knowledge.
Disposal of nuclear waste isn't to me a valid issue. That is easy, simple and should be cheap. Hysteria has made it something it shouldn't be.
As far as having those items handled by untrained people, the answer would be to train them. And pay them as skilled workers. When the US has needed teachers, incentives were put in place to create teachers. Same with engineers, and so on.
As far as the nuclear sources being diverted, that could be a problem. However, I suspect it could be packaged in such a way as to be unwieldy and impractical for any other use. There is one helluva lot of nuclear fuel in the world which seems to have been handled safely.