shouldn't we just get rid of the limits of our little knowledge and prepare to search for life as we DON'T know it?

Assuming that life is only possible is our condition is a very limitating mistake. In the early stages of an embrion our life is possible in an environment (the womb) that as an adult we couldn't live in (besides the size matter ;) )
That alone should keep our minds open to search for life in environments WE are not suited to live in. Shoot... we cannot live in water... we need to breath air... Fish cannot live outside the water...
Yes I know that we have some common denominators which are carbon and oxygen. But you will agre with me that those are dependent on the planet we live in. We are now looking for life on other planets (or moons, in this case), where conditions are different.... let's be open minded...