Of course it can.
It can also be undermined, which is being done even as we speak. (I remember habeas corpus...)
The question is, ought it to be? In the case of the First Ten, aka the Bill of Rights, I say no, no matter how inconvenient or dangerous some of the outcomes are.
We have plenty of unenforced gun laws that don't call for the repeal of the Second. We can really try to treat the disease using the tools we have before resorting to amputation.