"There are some historical trends that involve whole populations however. These might be more useful in predicting what the future might hold. If you want to know what major changes could happen, look at trends in reproductive technology... how many people do you think might be interested in that? Imagine a "home hospital". An automated kit that can diagnose illness, take x-rays, do blood tests, urinalysis, sequence your genome, splice genes, perform in-vitro fertilization, prescribe medication.... all without ever going to a clinic. Americans complain that socialized health care is communist. What if it came in a box that you could take home and do-it-yourself?

Might be some demand for that.

What would be the ramifications? "

In a sense you already have this.
No, we don't AI computers. Nor some of the others stuff you mention nor does it all come in some box- why would I want in-viro fertilization to be included in my box? And usually people buy stuff they are going use routinely. I could own a cement mixer, or I could rent one if I needed one.
It's true that we have a system of prescription drugs- not mention having prohibition on street drugs, but this social problem rather than technological. And probably, the freedom resulting from the internet will erode these types social restrictions.
Obviously a thing like socialize medicine could hinder this kind of process.

As far as space goes, you seem to equation space exploration with NASA. A common mistake, but I have sympathy for your distrust due to NASA's past efforts at space exploration.