Project Orion was cancelled around that time, Mars was one of it's goals:

The launch pad would have been composed of eight towers, each 250 feet high. The mass of the vehicle on takeoff would have been on the order of 10,000 TONS (28); most of this mass would have gone into orbit. The bomb units ejected on takeoff would have yielded 0.1 kiloton; initially the ejection rate would have been one per second. As the vehicle accelerated the rate would slow down and the yield would increase until 20-kiloton bombs would have been going off every ten seconds (29). The idea seems to have been for the vehicle to fly straight up until it cleared the atmosphere so as to minimize radioactive contamination.

At a time when the U.S. was struggling to put a single man into orbit aboard a modified military rocket, Taylor and Dyson were developing plans for a manned voyage of exploration through much of the solar system. The original Orion design called for 2000 pulse units, far more than enough to attain Earth escape velocity. "Our motto was 'Mars by 1965, Saturn by 1970'", recalls Dyson (30). Orion would have been more akin to the rocket ships of science fiction than to the cramped capsules of Gagarin and Glenn. One hundred and fifty people could have lived aboard in relative comfort; the useful payload would have been measured in thousands of tons (31). Orion would have been built like a battleship, with no need for the excruciating weight-saving measures adopted by chemically-propelled spacecraft.

Didn't work out, but can you imagine what could be done with a ship like that? 150 people in Saturn orbit for the last 33 years...