re: What if Evolution is wrong?
Without numbers it's difficult to decide. Remember that insects and small mammals have 1 or more generations per year so adaptation is quick. As to insects, there are so MANY offspring that huge numbers of permutations are achievable.
That said I don't doubt that there are some paradigm shifting surprises in store here. You raise some thoughtfull points. Whenever we think we have understood and mastered (sic) an aspect of nature, that perverse universe goes and makes fools of us.
Damn that simulation SW!