Drug companies
I suggest you read some other sources.
As just one example where Angell is wrong, private research funding by the pharmaceutical companies exceeds the entire budget of the NIH. The idea that most of the drug research is government-funded is crap.
While some basic research is done at universities, the cost of development and approval is paid for by drug companies, at a cost of about $800 million per drug. Approved at the end, or not.
Average profits of drug companies in the Fortune 1000 are about 16 percent.
Trying to pry some of the mythology on this subject loose is like trying to pry a limpet off a rock.