Standardization is a must.
Imagine building 500 nuclear power plants, each with two Westinghouse AP1000 reactors. Build them to be identical down to the light switches on the walls. Workers would not be able to tell one plant from another. Then you could create a national nuclear workers training program to train the workers to run them. Since they're identical, workers could transfer from one plant to another without needing any time to become acquainted with the new facility.
The builders could take some cues from Hoover Dam and give them a 30's era art deco feel.