Sometimes three -- Squanto played both sides against the middle.
Anyone interested in the history, not of Thanksgiving, but of the extraordinary interaction among the tribes of Massachusetts and the Pilgrims must read Mayflower: A Story of Courage, Community and War by Nathaniel Philbrick.
Philbrick manages, from original sources, to portray the people on all sides as sypathetic human beings dealing with new situations and alien neighbors in the contexts of their own cultures.