Drive is not enough, but it's most of it.
It wouldn't take long to come up with examples in all those categories of people who have done pretty well for themselves.
That's not to say disadvantages don't make it harder--often much harder--but they don't make it impossible, either.
The proof from the other direction is that it wouldn't take long to come up with examples of people who started out with all the advantages of wealth, good looks, and health, and wound up complete wastes of oxygen.
Right now, our culture has swung way too far in the "victim mentality" direction. There's a reason for this.