Yes & You Need To Figure That Into The Cost Of Infrastructure
It doesn't make sense to make huge investments in ineficient infrastructure when you can reap far greater rewards for the same investment.
Look at the relative abundance of water on Mars and the Moon.
Look at the relative abundance of carbon on Mars and the Moon.
Look at the relative abundance of nitrogen on Mars and the Moon.
Then look at the form of these materials as well and the ease of processing them.
Regards,
Mark