Something is significant, recognized, beautiful, interesting because...
we think it is all of this.
Because it's us humans, at this moment in space and time, who find it so.
But to other lifeforms on Earth, it's irrelevent (don't dogs see only in black and white and therefore miss all those things we see in color, but can't they smell a lot more than we can, therefore we miss what they experience?) and how about possible life elsewhere?
We can relate to our own experience and it really is minute and therefore must admit what we find significant is nevertheless rather relative.